Among the finest actor-director duos in cinematic history, Robert De Niro and Martin Scorsese have collaborated 10 times during their decorated careers. Their most recent venture was the sprawling true-crime epic Killers of the Flower Moon in 2023, which earned both Academy Award nods for their excellent supporting performance and direction, respectively. Along with The Irishman, Killers of the FlowerMoon is also the longest-running film De Niro and Scorsese have made together, with their 1995 crime classic set to leave Netflix soon, ranking right behind.